ABPDB

Basic Information

ID	DRAMP29141
Sequence	GLKEVAHSAKKFAKGFISGLTGS
Length	23
Name	Pxt‐3
Source	Xenopus tropicalis
Activity	Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal
Pathogen	[Ref.25312021]Gram-negative bacteria:Escherichia coli DH5α(Not active up to 150 µg/ml);##Gram-positive bacteria:Staphylococcus aureus JCM 2151(Not active up to 150 µg/ml).##[Ref.23935531]Gram-negative bacteria:Escherichia coli ATCC 25922(MIC=64 µm);Pseudomonas aeruginosa ATCC 15692(MIC >256 µM);##Gram-positive bacteria:Staphylococcus aureus ATCC 25923(MIC >256 µM);Micrococcus luteus(MIC=32 µM);##Fungi:Saccharomyces cerevisiae(MIC=128 µM);##Parasite:Trypanosoma brucei(LC95=8->256 µM).
Hemolytic Activity	[Ref.25312021]0.2% Hemolysis against Rat erythrocytes at 20 µM.##[Ref.23935531] Hemolysis against Mouse erythrocytes (HC50>256 µm).
Cytotoxicity	[Ref.23935531]Cytotoxicity against T-lymphocytes(IC50>256 µM).
N-terminal Modification	Free
C-terminal Modification	Free
Linear/Cyclic/Branched	Linear
Uniprot
PDB
3D View
PDB Download	Download PDB Predicted by Alphafold2
PubMed ID	25312021, 23935531

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