| ID | dbAMP00487 |
|---|---|
| Sequence | AQEPVKGPVSTKPGSCPIILIRCAMLNPPNRCLKDTDCPGIKKCCEGSCGMACFVPQ |
| Length | 57 |
| Name | Homo sapiens&&ELAF_HUMAN&&Elafin |
| Source | Homo sapiens |
| Activity | Antibacterial |
| Pathogen | Staphylococcus aureus C1705 (40-50% Killing=25µM)&&Pseudomonas aeruginosa PAO1 (90-100% Killing=2.5µM)&&HIV-1 (IC50=0.0006±0.0001µg/ml)&&HIV-1 (IC50=0.0003±0.0002µg/ml)&&Escherichia coli ATCC 35218 |
| Hemolytic Activity | Not included yet |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P19957 |
| PDB | 2REL |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 15489334, 16336202 |
Physicochemical Properties
| Residues | 57 |
|---|---|
| Sequence | AQEPVKGPVSTKPGSCPIILIRCAMLNPPNRCLKDTDCPGIKKCCEGSCGMACFVPQ |
| Molecular Weight | 6007.171 |
| Grand Average of Hydropathy | -0.019 |
| Isoelectric Point | 8.509 |
| Charge at pH 7.4 | 2.402 |
| Secondary Structure | Helix: 0.193, Turn: 0.316, Sheet: 0.175 |
| Instability Index | 57.377 |
| Aromaticity | 0.018 |