| ID | dbAMP01442 |
|---|---|
| Sequence | ELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK |
| Length | 37 |
| Name | Human Defensin beta 104A (hBD-4)&&Homo sapiens&&D104A_HUMAN |
| Source | Homo sapiens |
| Activity | Antibacterial |
| Pathogen | Streptococcus pneumoniae ATCC 33400 (MIC=>100µg/ml)&&Staphylococcus carnosus TM300 (MIC=>72µg/ml)&&Staphylococcus carnosus TM300 (MIC=4.5µg/ml)&&Staphylococcus aureus NCTC 8530 (LC=12µM)&&Staphylococcus aureus ATCC 25923 (MIC=>100µg/ml)&&Saccharomyces cer |
| Hemolytic Activity | Not included yet |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | Q8WTQ1 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 11481241, 15489334, 11481241 |
Physicochemical Properties
| Residues | 37 |
|---|---|
| Sequence | ELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK |
| Molecular Weight | 4372.097 |
| Grand Average of Hydropathy | -0.93 |
| Isoelectric Point | 9.499 |
| Charge at pH 7.4 | 6.507 |
| Secondary Structure | Helix: 0.189, Turn: 0.162, Sheet: 0.162 |
| Instability Index | 50.122 |
| Aromaticity | 0.081 |