| ID | DRAMP00162 |
|---|---|
| Sequence | GNAACVIGCIGSCVISEGIGSLVGTAFTLG |
| Length | 30 |
| Name | Thuricin CDalpha (Trn-alpha; one peptide of Thuricin CD; Bacteriocin) |
| Source | Bacillus thuringiensis DPC 6431 (Gram-positive bacteria) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+ |
| Pathogen | Gram-positive bacteria: Clinical Clostridium difficile isolates (MIC in the range of nM) and Listeria monocytogenes, Lactobacillus fermentum. |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | F5AT07 |
| PDB | 2L9X |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 20435915, 21526839 |
Physicochemical Properties
| Residues | 30 |
|---|---|
| Sequence | GNAACVIGCIGSCVISEGIGSLVGTAFTLG |
| Molecular Weight | 2770.206 |
| Grand Average of Hydropathy | 1.343 |
| Isoelectric Point | 4.05 |
| Charge at pH 7.4 | -1.515 |
| Secondary Structure | Helix: 0.333, Turn: 0.367, Sheet: 0.200 |
| Instability Index | 25.253 |
| Aromaticity | 0.033 |