Basic Information

IDDRAMP00393
SequenceIQCGESCVWIPCISSAWGCSCKNKICSS
Length28
NameHedyotide B2 (hB2; Uncyclotides; Plants)
SourceHedyotis biflora (aerial tissues)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacterium: Escherichia coli (MIC>80 µM);##Gram-positive bacteria: Streptococcus salivarius(MIC>80 µM), Staphylococcus epidermidis (MIC>80 µM), Streptococcus aureus (MIC>80 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID21979955

Physicochemical Properties

Residues28
SequenceIQCGESCVWIPCISSAWGCSCKNKICSS
Molecular Weight2993.504
Grand Average of Hydropathy0.418
Isoelectric Point7.774
Charge at pH 7.40.407
Secondary StructureHelix: 0.250, Turn: 0.357, Sheet: 0.071
Instability Index43.486
Aromaticity0.071

Similar Structure Search

Candidates based on structure

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