Basic Information
| ID | DRAMP00798 |
|---|
| Sequence | GIPCGESCVFIPCITGAIGCSCKSKVCYRN |
|---|
| Length | 30 |
|---|
| Name | Cliotide T4 (cT4; Plant defensin) |
|---|
| Source | Clitoria ternatea (Butterfly pea) |
|---|
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Anti-cancer |
|---|
| Pathogen | [Ref.21596752]Gram-positive bacteria: Staphylococcus aureus ATCC12600, Enterococcus faecalis ATCC 47077 (less active);##Gram-negative bacteria: Escherichia coli ATCC 700926 (MIC=1.3 µM), Pseudomonas aeruginosa ATCC 39018 (MIC=1.9 µM), Klebsiella pneumonia ATCC 13883 (MIC=1.5 µM). |
|---|
| Hemolytic Activity | [Ref.21596752] HD50 = 8.4 μM against human red blood cells |
|---|
| Cytotoxicity | [Ref.21596752] IC50=0.6 µM against HeLa cells. |
|---|
| N-terminal Modification | Free |
|---|
| C-terminal Modification | Free |
|---|
| Linear/Cyclic/Branched | Cyclic |
|---|
| Uniprot |
|
|---|
| PDB |
|
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 21596752 |
|---|
