Basic Information
| ID | DRAMP00795 |
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| Sequence | GIPCGESCVFIPCITAAIGCSCKSKVCYRN |
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| Length | 30 |
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| Name | Cliotide T1 (cT1; Plant defensin) |
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| Source | Clitoria ternatea (Butterfly pea) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Anti-cancer |
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| Pathogen | [Ref.21596752]Gram-positive bacteria: Staphylococcus aureus ATCC12600, Enterococcus faecalis ATCC 47077 (less active);##Gram-negative bacteria: Escherichia coli ATCC 700926 (MIC=1.1 µM), Pseudomonas aeruginosa ATCC 39018 (MIC=2.7 µM), Klebsiella pneumonia ATCC 13883 (MIC=4.7 µM). |
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| Hemolytic Activity | [Ref.21596752] HD50 = 7.1 μM against human red blood cells |
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| Cytotoxicity | [Ref.21596752] IC50=0.6 µM against HeLa cells. |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 21596752 |
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