Basic Information

IDDRAMP01585
SequenceGLFSVLGSVAKHLLPHVVPVIAEKL
Length25
NameCaerin-1.18 (Frogs, amphibians, animals)
SourceLitoria gracilenta (Dainty green tree frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Bacillus cereus (MIC=50 µg/ml), Leuconostoc lactis (MIC=25 µg/ml), Listeria innocua (MIC=12 µg/ml), Micrococcus luteus (MIC=12 µg/ml), Staphylococcus aureus ATCC 25923 (MIC=12 µg/ml), Staphylococcus aureus ATCC 29213 (MIC=12 µg/ml), Staphylococcus epidermidis (MIC=25 µg/ml), Streptococcus uberis (MIC=25 µg/ml);##Gram-negative bacteria: Pasteurella multocida (MIC=50 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.16554081]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P0C2A7
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16554081

Physicochemical Properties

Residues25
SequenceGLFSVLGSVAKHLLPHVVPVIAEKL
Molecular Weight2624.17
Grand Average of Hydropathy1.104
Isoelectric Point8.606
Charge at pH 7.40.627
Secondary StructureHelix: 0.480, Turn: 0.240, Sheet: 0.320
Instability Index29.316
Aromaticity0.04

Similar Structure Search

Candidates based on structure

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