Basic Information

IDDRAMP01717
SequenceSLGSFLKGVGTTLASVGKVVSDQFGKLLQAGQ
Length32
NameDermatoxin (Frogs, amphibians, animals)
SourcePhyllomedusa bicolor (Two-colored leaf frog) (Rana bicolor)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Bacillus megaterium, Corynebacterium glutamicumm, Staphylococcus aureus (++);##Gram-negative bacteria: mollicutes Acholeplasma laidlawii, Spiroplasma melliferum (++); Burkholderia cepacia, Pseudomonas aeruginosa, Salmonella typhimurium and S. meliloti (+).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q9PT75, P81566
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10880984

Physicochemical Properties

Residues32
SequenceSLGSFLKGVGTTLASVGKVVSDQFGKLLQAGQ
Molecular Weight3193.647
Grand Average of Hydropathy0.384
Isoelectric Point9.7
Charge at pH 7.41.246
Secondary StructureHelix: 0.344, Turn: 0.312, Sheet: 0.219
Instability Index-6.359
Aromaticity0.062

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.