Basic Information

IDDRAMP01737
SequenceFFPIVGKLLFGLL
Length13
NameTemporin-ALj (Frogs, amphibians, animals)
SourceAmolops loloensis
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.19843479]Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=7.5 µg/mL), Bacillus pumilus (MIC=15 µg/mL), Bacillus cereus (MIC=75 µg/mL);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=15 µg/mL), Bacillus dysenteriae (MIC=30 µg/mL), Acinetobacter calcoaceticus (MIC=60 µg/mL), Psecdomonas aeruginosa (MIC=7.5 µg/mL);##Yeast: Candida albicans ATCC2002 (MIC=5 µg/mL).
Hemolytic Activity[Ref:19843479]19% hemolytic activity at 100 μg/mL against rabbit red blood cells.
Cytotoxicity[Ref.19843479]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19843479

Physicochemical Properties

Residues13
SequenceFFPIVGKLLFGLL
Molecular Weight1463.846
Grand Average of Hydropathy2
Isoelectric Point8.75
Charge at pH 7.40.555
Secondary StructureHelix: 0.692, Turn: 0.231, Sheet: 0.308
Instability Index-2.077
Aromaticity0.231

Similar Structure Search

Candidates based on structure

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