Basic Information

IDDRAMP01764
SequenceFLPILGKLLSGIL
Length13
NameTemporin-1TGa (Frogs, amphibians, animals)
SourceRana tagoi (Tago frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacterium: Staphylococcus aureus (MIC=15 µM);##Gram-negative bacterium: Escherichia coli (MIC>100 µM).##Yeast: Candida albicans.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.12804591]No cytotoxicity information found##[Ref.16675060]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot Q2PGA8
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12804591, 16675060

Physicochemical Properties

Residues13
SequenceFLPILGKLLSGIL
Molecular Weight1383.76
Grand Average of Hydropathy1.823
Isoelectric Point8.75
Charge at pH 7.40.555
Secondary StructureHelix: 0.615, Turn: 0.308, Sheet: 0.385
Instability Index34.085
Aromaticity0.077

Similar Structure Search

Candidates based on structure

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