Basic Information
| ID | DRAMP01777 |
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| Sequence | FLSHIAGFLSNLFGK |
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| Length | 15 |
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| Name | Temporin-1Sc (Temporin-SHc; Frogs, amphibians, animals) |
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| Source | Pelophylax saharicus (Sahara frog) (Rana saharica) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.18584916]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=10 µg/ml), Enterococcus faecalis ATCC 29212 (MIC>80 µg/ml), Bacillus megaterium (MIC=4 µg/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=161 µg/ml), Escherichia coli ATCC 35218 (MIC>80 µg/ml), Pseudomonas aeruginosa ATCC 27853 (MIC>161 µg/ml);##Fungi: Aspergillus flavus (MIC=10 µg/ml), Candida albicans ATCC 90028 (MIC=20 µg/ml), Candida parapsilosis ATCC 22019 (MIC=20 µg/ml), Saccharomyces cerevisiae (MIC=10 µg/ml). |
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| Hemolytic Activity | [Ref:18584916]LC50>80 μM against human erythrocytes |
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| Cytotoxicity | [Ref.18584916]No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
B3KYH6 |
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| PDB |
|
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 18584916 |
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