| ID | DRAMP29132 |
|---|---|
| Sequence | GLLGKLLKIAAKVGSNLL |
| Length | 18 |
| Name | XT-7 [P5K] |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal |
| Pathogen | [Ref.18554256]Gram-negative bacteria:Escherichia coli ATCC 25726(MIC=12.5 µM);##Gram-positive bactria:Staphylococcus aureus ATCC 25923(MIC=3 µM);##Fungi:Candida albicans ATCC 900280(MIC=6 µM);##Cancer:human hepatoma‐derived cells HepG2 (LC50=14 µM). |
| Hemolytic Activity | [Ref.18554256]Hemolysis against human erythrocytes (LC50=15 µM). |
| Cytotoxicity | [Ref.18554256]No cytotoxicity information found. |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Linear/Cyclic/Branched | Linear |
| Uniprot | P84381 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 18554256 |
Physicochemical Properties
| Residues | 18 |
|---|---|
| Sequence | GLLGKLLKIAAKVGSNLL |
| Molecular Weight | 1808.256 |
| Grand Average of Hydropathy | 0.994 |
| Isoelectric Point | 10.302 |
| Charge at pH 7.4 | 2.55 |
| Secondary Structure | Helix: 0.444, Turn: 0.278, Sheet: 0.444 |
| Instability Index | -18.856 |
| Aromaticity | 0 |