ABPDB

Basic Information

ID	DRAMP29136
Sequence	GLLGPLLKIAAKVGSKLL
Length	18
Name	XT-7 [N16K]
Source	Synthetic construct
Activity	Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Antifungal
Pathogen	[Ref.23094651]Gram-negative bacteria:Escherichia coli ATCC 25922(MIC=6.3 µM).##[Ref.18554256]Gram-negative bacteria:Escherichia coli ATCC 25726(MIC=12.5 µM);##Gram-positive bactria:Staphylococcus aureus ATCC 25923(MIC=3 µM);##Fungi:Candida albicans ATCC 900280(MIC=12.5 µM);##Cancer: human hepatoma‐derived cells HepG2 (LC50=22 µM).
Hemolytic Activity	[Ref.23094651]50% hemolysis against rat erythrocytes at 142 µM.##[Ref.18554256]Hemolysis against human erythrocytes (LC50=80 µM).
Cytotoxicity	[Ref.18554256]No cytotoxicity information found.
N-terminal Modification	Free
C-terminal Modification	Amidation
Linear/Cyclic/Branched	Linear
Uniprot	P84381
PDB
3D View
PDB Download	Download PDB Predicted by Alphafold2
PubMed ID	23094651, 18554256

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