Basic Information
| ID | DRAMP02135 |
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| Sequence | GFLGSLLKTGLKVGSNLL |
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| Length | 18 |
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| Name | Antimicrobial peptide 6 (XT-6; Frogs, amphibians, animals) |
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| Source | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.11738090]Gram-positive bacterium: Staphylococcus aureus (MIC=5 µM);##Gram-negative bacterium: Escherichia coli (MIC=5 µM);##Yeast: Candida albicans (MIC=40 µM);##Clinical isolates: Staphylococcus aureus 8325 (MIC=6 µM), Staphylococcus aureus (MRSA) (MIC=7 µM), Staphylococcus epidermidis 1420129 (MIC=3 µM), S. saprophyticus 1950556 (MIC=13 µM), Escherichia coli 25922 (MIC=6 µM), Streptococcus group C 1541035 (MIC=3 µM), Shigella sonnei 1840187 (MIC=35 µM), Pseudomonas aeruginosa 0380972 (MIC=60 µM), Enterobacter cloacae 1441323 (MIC=35 µM) |
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| Hemolytic Activity | [Ref.11738090]HC50=70 μM against human erythrocytes |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
P84386 |
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| PDB |
|
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 11738090 |
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