Basic Information

IDDRAMP20802
SequenceGLGSVLGKALKIGANLL
Length17
NameCPF-AM1 (caerulein precursor fragment-AM1, frogs, amphibians, animals)
SourceXenopus amieti (skin secretions, Africa)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.20226221] Gram-positive bacteria: Staphylococcus aureus (MIC>200μM) ;##Gram-negative bacteria: Escherichia coli (MIC>200μM).
Hemolytic Activity[Ref.20226221] LC50>200μM against human red blood cells
Cytotoxicity[Ref.20226221] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID20226221

Physicochemical Properties

Residues17
SequenceGLGSVLGKALKIGANLL
Molecular Weight1623.977
Grand Average of Hydropathy1.035
Isoelectric Point10.003
Charge at pH 7.41.552
Secondary StructureHelix: 0.412, Turn: 0.353, Sheet: 0.412
Instability Index-10.565
Aromaticity0

Similar Structure Search

Candidates based on structure

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