ABPDB

Basic Information

ID	DRAMP29147
Sequence	NLLGSLLKTGLKVGSNLL
Length	18
Name	Pxt‐12(CPF-St7)
Source	Xenopus tropicalis
Activity	Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-,Antifungal
Pathogen	[Ref.26802742]Gram-negative bacteria:Escherichia coli NBRC 14237(MIC<12.5 µM);Pseudomonas aeruginosa NBRC 12582(MIC<50 µM);##Gram-positive bacteria:Staphylococcus aureus NBRC 12732(MIC<12.5 µM);Micrococcus luteus NBRC 12708(MIC<50 µM);##Fungi:Candida albicans NBRC 1594(ND). ##[Ref.23935531]Gram-negative bacteria:Escherichia coli ATCC 25922(MIC=128 µM);Pseudomonas aeruginosa ATCC 15692(MIC >256 µM);##Gram-positive bacteria:Staphylococcus aureus ATCC 25923(MIC=32 µM);Micrococcus luteus(MIC=2 µM);##Fungi:Saccharomyces cerevisiae(MIC=64 µM);##Parasite:Trypanosoma brucei(LC95=2-64 µM).
Hemolytic Activity	[Ref.26802742]0% Hemolysis against Rat erythrocytes at 50 µM.##[Ref.23935531]Hemolysis against Mouse erythrocytes(IC50=256 µM).
Cytotoxicity	[Ref.23935531]Cytotoxicity against T-lymphocytes(IC50=128 µM).
N-terminal Modification	Free
C-terminal Modification	Amidation
Linear/Cyclic/Branched	Linear
Uniprot	P84386
PDB
3D View
PDB Download	Download PDB Predicted by Alphafold2
PubMed ID	26802742, 23935531

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