Basic Information

IDDRAMP02246
SequenceSMLSVLKNLGKVGLGLVACKINKQC
Length25
NameRanatuerin-1C (Ranatuerin 1C; Frogs, amphibians, animals)
SourceRana clamitans (Green frog) (Lithobates clamitans)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.10822101] Gram-positive bacterium: Staphylococcus aureus (MIC=55 μM);##Gram-negative bacterium: Escherichia coli (MIC=1.5 μM).##Yeast: Candida albicans (MIC=58 μM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys19 and Cys25)
Linear/Cyclic/BranchedCyclic
Uniprot P82875
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10822101

Physicochemical Properties

Residues25
SequenceSMLSVLKNLGKVGLGLVACKINKQC
Molecular Weight2617.246
Grand Average of Hydropathy0.636
Isoelectric Point9.7
Charge at pH 7.43.194
Secondary StructureHelix: 0.360, Turn: 0.280, Sheet: 0.280
Instability Index26.108
Aromaticity0

Similar Structure Search

Candidates based on structure

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