| ID | DRAMP21467 |
|---|---|
| Sequence | GLLDFLKAAGKGLVSNLLEK |
| Length | 20 |
| Name | P3-Ll-2085 (De Novo Synthesis) |
| Source | Leptodactylus latrans (Anura: Leptodactylidae) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.30423858] Gram-positive bacteria:Staphylococcus aureus ATCC 25923(MIC=15μM);##Gram-negative bacteria:Escherichia coli ATCC 25922(MIC=15μM) |
| Hemolytic Activity | [Ref.30423858] 100% hemolysis MHC=40μM against human blood cells |
| Cytotoxicity | [Ref.30423858] No cytotoxicity information found. |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 30423858 |
Physicochemical Properties
| Residues | 20 |
|---|---|
| Sequence | GLLDFLKAAGKGLVSNLLEK |
| Molecular Weight | 2086.474 |
| Grand Average of Hydropathy | 0.46 |
| Isoelectric Point | 8.498 |
| Charge at pH 7.4 | 0.552 |
| Secondary Structure | Helix: 0.400, Turn: 0.250, Sheet: 0.450 |
| Instability Index | -7.005 |
| Aromaticity | 0.05 |
