Basic Information
| ID | DRAMP01789 |
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| Sequence | FLSSIGKILGNLL |
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| Length | 13 |
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| Name | Temporin-1Va (Temporin 1Va; Frogs, amphibians, animals) |
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| Source | Rana virgatipes (Ranidae) (Aquarana) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.15996769]Gram-positive bacteria: Staphylococcus aureus NCTC8325 (MIC=10 µM), S. aureus (MRSA) T7/20 (MIC=20 µM), S. epidermidis RP62A (MIC=20 µM), Enterococcus faecalis ATCC 29212 (MIC=40 µM), Streptococcus group B HNTCC 80130 (MIC=20 µM);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=40 µM), Klebsiella pneumoniae KK3 9904 (MIC=80 µM), Pseudomonas aeruginosa ATCC 27853 (MIC=160 µM), Enterobacter cloacae HNTCC 53001 (MIC=40 µM);##Yeast: Candida albicans ATCC 90028 (MIC=160 µM). |
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| Hemolytic Activity | [Ref:15996769]LD50=120 μM against washed human erythrocytes |
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| Cytotoxicity | [Ref.15996769]No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 15996769 |
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