Basic Information

IDDRAMP01811
SequenceFLKPLFNAALKLLP
Length14
NameTemporin-Ra (Frogs, amphibians, animals)
SourceRana ridibunda (marsh frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli (MIC=24.2 µg/ml), Klebsiella pneumoniae PTCC 1388 (MIC=31.2 µg/ml);##Gram-positive bacteria: Streptococcus dysgalactiae PTCC 1074 (MIC=33.2 µg/ml), Streptococcus agalactiae PTCC 1365 (MIC=24.7 µg/ml) and Staphylococcus aureus PTCC 1431 (MIC=35.2 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.21956830]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID21956830

Physicochemical Properties

Residues14
SequenceFLKPLFNAALKLLP
Molecular Weight1584.984
Grand Average of Hydropathy0.979
Isoelectric Point10.003
Charge at pH 7.41.552
Secondary StructureHelix: 0.500, Turn: 0.214, Sheet: 0.500
Instability Index-0.536
Aromaticity0.143

Similar Structure Search

Candidates based on structure

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