Basic Information
| ID | DRAMP01303 |
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| Sequence | FLSLIPHAINAVSALANHG |
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| Length | 19 |
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| Name | Phylloseptin-3 (PS-3; Frogs, amphibians, animals) |
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| Source | Phyllomedusa hypochondrialis (Orange-legged leaf frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [ATCC Strains]: Gram-positive bacteria: S. aureus (MIC=32.9 µM);##Gram-negative bacteria: Escherichia coli (MIC=65.6 µM), Klebsiella pneumoniae (MIC=65.6 µM), Pseudomonas aeruginosa (MIC=65.6 µM). NOTE: Initial inoculum of 108 cells/Ml.##[Wild Type]: Gram-positive bacteria: S. aureus (MIC=8.2 µM), S. agalactiae (MIC=4.1 µM);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=32.8 µM), A. calcoaceticus (MIC=4.1 µM).##Fungi: Candida albicans (MIC=8.2 µM). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | [Ref.15752569]No cytotoxicity information found##[Ref.18656510]No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
P84568 |
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| PDB |
2JQ1 |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 15752569, 18656510 |
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