Basic Information

IDDRAMP01834
SequenceFLNALKNFAKTAGKRLKSLLN
Length21
NameCyanophlyctin (Frogs, amphibians, animals)
SourceEuphlyctis cyanophlyctis (Skittering frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Swiss_Prot Entry C0HJB8]Gram-negative bacteria: Escherichia coli HP101BA (MIC=6.4 µM), Klebsiella pneumoniae PTCC1388 (MIC=7.3 µM);##Gram-positive bacteria: Micrococcus luteus PTCC1625 (MIC=4.7 µM), Staphylococcus aureus PTCC1431 (MIC=5.3 µM).
Hemolytic Activity[Ref.Int J Pept Res Ther(2012)18;107.]<3% hemolytic activity at 60 µg/ml against human red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot C0HJB8
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed IDPubMed ID is not available

Physicochemical Properties

Residues21
SequenceFLNALKNFAKTAGKRLKSLLN
Molecular Weight2347.8
Grand Average of Hydropathy-0.119
Isoelectric Point11.334
Charge at pH 7.44.547
Secondary StructureHelix: 0.333, Turn: 0.238, Sheet: 0.381
Instability Index5.762
Aromaticity0.095

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Candidates based on structure

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