Basic Information
| ID | DRAMP02047 |
|---|
| Sequence | ILPFVAGVAAEMMEHVYCAASKKC |
|---|
| Length | 24 |
|---|
| Name | Brevinin-1-OR8 (Frogs, amphibians, animals) |
|---|
| Source | Odorrana rotodora (Chinese odorous frog) |
|---|
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
|---|
| Pathogen | Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=13.1 µg/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=52.4 µg/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=26.2 µg/ml).##Yeast: Candida albicans (MIC=13.1 µg/ml). |
|---|
| Hemolytic Activity | [Ref.22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 μg/mL. |
|---|
| Cytotoxicity | No cytotoxicity information found |
|---|
| N-terminal Modification | Free |
|---|
| C-terminal Modification | Cyclization (Cys18 and Cys24) |
|---|
| Linear/Cyclic/Branched | Cyclic |
|---|
| Uniprot |
|
|---|
| PDB |
|
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 22029824 |
|---|
