Basic Information

IDDRAMP01386
SequenceVIPFVASVAAEMMQHVYCAASKKC
Length24
NameOdorranain-P1a (OdP1a; Brevinin-1HS1; Brevinin-1-OA2; Frogs, amphibians, animals)
SourceOdorrana grahami (Yunnanfu frog) (Rana grahami)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=3.50 μg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=3.50 μg/ml), Bacillus subtilis (MIC=1.75 μg/ml).##Yeast: Candida albicans (MIC=1.75 μg/ml).
Hemolytic Activity[Ref.17272268] RCH=11.2 ± 2.9% against rabbit red blood cells. RCH, red cell hemolysis.
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot A6MBQ8, A6MBQ6
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17272268

Physicochemical Properties

Residues24
SequenceVIPFVASVAAEMMQHVYCAASKKC
Molecular Weight2584.108
Grand Average of Hydropathy0.808
Isoelectric Point8.016
Charge at pH 7.40.504
Secondary StructureHelix: 0.292, Turn: 0.125, Sheet: 0.333
Instability Index8.925
Aromaticity0.083

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.