Basic Information

IDDRAMP02051
SequenceILPFVAGVAAEMMQHVYCAASKKC
Length24
NameLividin-1 (Brevinin-1-OR2; Frogs, amphibians, animals)
SourceOdorrana rotodora (Chinese odorous frog) (Odorrana livida)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Escherichia coli ATCC 25922 (MIC=5.8 µg/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=11.6 µg/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=11.6 µg/ml).##Yeast: Candida albicans (MIC=5.8 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys18 and Cys24)
Linear/Cyclic/BranchedCyclic
Uniprot Q2UXR4
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16713657, 22029824

Physicochemical Properties

Residues24
SequenceILPFVAGVAAEMMQHVYCAASKKC
Molecular Weight2568.109
Grand Average of Hydropathy0.808
Isoelectric Point8.043
Charge at pH 7.40.539
Secondary StructureHelix: 0.292, Turn: 0.125, Sheet: 0.375
Instability Index26.175
Aromaticity0.083

Similar Structure Search

Candidates based on structure

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