Basic Information

IDDRAMP02052
SequenceSFLDTLKNLAISAAKGAGQSVLSTLSCKLSKTC
Length33
NameLividin-2 (Brevinin-2-OR8; Frogs, amphibians, animals)
SourceOdorrana rotodora (Chinese odorous frog) (Odorrana livida)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Escherichia coli ATCC 25922 (MIC=13.1 µg/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=13.1 µg/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=13.1 µg/ml).##Yeast: Candida albicans (MIC=13.1 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys27 and Cys33)
Linear/Cyclic/BranchedCyclic
Uniprot Q2UXR3
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16713657, 22029824

Physicochemical Properties

Residues33
SequenceSFLDTLKNLAISAAKGAGQSVLSTLSCKLSKTC
Molecular Weight3356.907
Grand Average of Hydropathy0.385
Isoelectric Point9.303
Charge at pH 7.42.195
Secondary StructureHelix: 0.273, Turn: 0.273, Sheet: 0.303
Instability Index18.045
Aromaticity0.03

Similar Structure Search

Candidates based on structure

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