Basic Information

IDDRAMP02421
SequenceACHAHCQSVGRRGGYCGNFRMTCYCY
Length26
NameHlgut-defensin (H. longicornis midgut defensin; Ticks, Arthropods, animals)
SourceHaemaphysalis longicornis (Bush tick)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus (MIC=5-25 mg/mL);##Gram-negative bacterium: Escherichia coli (MIC=10-25 mg/mL).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot A4GUC3
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17521774

Physicochemical Properties

Residues26
SequenceACHAHCQSVGRRGGYCGNFRMTCYCY
Molecular Weight2944.36
Grand Average of Hydropathy-0.342
Isoelectric Point8.784
Charge at pH 7.42.551
Secondary StructureHelix: 0.192, Turn: 0.231, Sheet: 0.115
Instability Index56.615
Aromaticity0.154

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.