| ID | DRAMP02430 |
|---|---|
| Sequence | GLHKVMREVLGYERNSYKKFFLR |
| Length | 23 |
| Name | Ixosin (Ticks, Arthropods, animals) |
| Source | Ixodes sinensis (Hard tick) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram-, Antifungal |
| Pathogen | [Ref.16087274]Gram-postive bacteria: Staphylococcus aureus (MIC=3.7 µg/ml);##Gram-negative bacteria: Escherichia coli (MIC=30 µg/ml);##Fungi: Candida albicans (MIC=7.5 µg/ml). |
| Hemolytic Activity | [Ref.16087274]Little hemolytic activity on rabbit red blood cells up to 50 μg/mL |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | Q2LKX9 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 16087274 |
Physicochemical Properties
| Residues | 23 |
|---|---|
| Sequence | GLHKVMREVLGYERNSYKKFFLR |
| Molecular Weight | 2871.364 |
| Grand Average of Hydropathy | -0.687 |
| Isoelectric Point | 10.161 |
| Charge at pH 7.4 | 3.584 |
| Secondary Structure | Helix: 0.391, Turn: 0.174, Sheet: 0.261 |
| Instability Index | 19.661 |
| Aromaticity | 0.174 |