Basic Information

IDDRAMP02653
SequenceACYCRIPACLAGERRYGTCFYLGRVWAFCC
Length30
NameNeutrophil defensin 1 (RMAD-1; primates, mammals, animals)
SourceMacaca mulatta (Rhesus macaque)
ActivityAntimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Staphylococcus aureus and Listeria monocytogenes;##Gram-negative bacterium: Escherichia coli.##Fungi: Cryptococcus neoformans.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P60030
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10531277

Physicochemical Properties

Residues30
SequenceACYCRIPACLAGERRYGTCFYLGRVWAFCC
Molecular Weight3453.095
Grand Average of Hydropathy0.477
Isoelectric Point8.678
Charge at pH 7.42.454
Secondary StructureHelix: 0.333, Turn: 0.133, Sheet: 0.233
Instability Index65.104
Aromaticity0.2

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