Basic Information

IDDRAMP02659
SequenceACYCRIPACLAGERRYGTCFYRRRVWAFCC
Length30
NameNeutrophil defensin 3 (RMAD-3; primates, mammals, animals)
SourceMacaca mulatta (Rhesus monkey)
ActivityAntimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Staphylococcus aureus and Listeria monocytogenes;##Gram-negative bacteria: Escherichia coli.##Fungi: Cryptococcus neoformans.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P60031, P82318
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10531277

Physicochemical Properties

Residues30
SequenceACYCRIPACLAGERRYGTCFYRRRVWAFCC
Molecular Weight3595.258
Grand Average of Hydropathy0.063
Isoelectric Point9.182
Charge at pH 7.44.454
Secondary StructureHelix: 0.300, Turn: 0.100, Sheet: 0.200
Instability Index97.654
Aromaticity0.2

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