Basic Information

IDDRAMP02654
SequenceACYCRIPACLAGERRYGTCFYMGRVWAFCC
Length30
NameNeutrophil defensin 2 (RMAD-2; primates, mammals, animals)
SourceMacaca mulatta (Rhesus macaque)
ActivityAntimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Staphylococcus aureus and Listeria monocytogenes;##Gram-negative bacterium: Escherichia coli.##Fungi: Cryptococcus neoformans.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P82317
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10531277

Physicochemical Properties

Residues30
SequenceACYCRIPACLAGERRYGTCFYMGRVWAFCC
Molecular Weight3471.133
Grand Average of Hydropathy0.413
Isoelectric Point8.678
Charge at pH 7.42.454
Secondary StructureHelix: 0.300, Turn: 0.133, Sheet: 0.233
Instability Index79.75
Aromaticity0.2

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