Basic Information

IDDRAMP02840
SequenceFKCRRWQWRMKKLGAPSITCVRRAF
Length25
NameLactoferricin B (Lfcin B; mammals, animals)
SourceBos taurus (Bovine)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.8980754] Gram-negative bacteria: Escherichia coli L361 (MIC=4 µM or 12.5 µg/ml), Salmonella Salford (MIC=4 µM or 12.5 µg/ml), Escherichia coli O:9 (MIC=6 µM or 18.8 µg/ml), Pseudomonas fluorescens (MIC=10 µM or 31.3 µg/ml) ;##Gram-positive bacteria: Listeria monocytogenes (MIC=2 µM or 6.3 µg/ml), Staphylococcus aureus (MIC=6 µM or 18.8 µg/ml), Bacillus cereus (MIC=6 µM or 18.8 µg/ml)
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot P24627, E6YCQ7, B3VTM3, B9VPZ5, C7FE01, Q6LBN7, Q19KS1
PDB 1LFC
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID8980754, 9521752, 1490908

Physicochemical Properties

Residues25
SequenceFKCRRWQWRMKKLGAPSITCVRRAF
Molecular Weight3125.789
Grand Average of Hydropathy-0.576
Isoelectric Point11.84
Charge at pH 7.47.501
Secondary StructureHelix: 0.280, Turn: 0.120, Sheet: 0.160
Instability Index77.924
Aromaticity0.16

Similar Structure Search

Candidates based on structure

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