| ID | DRAMP02912 |
|---|---|
| Sequence | RGLRRLGRKIAHGVKKYGPTVLRIIRIAG |
| Length | 29 |
| Name | SMAP-29 (Cathelin-related peptide SC5; Myeloid antibacterial peptide MAP-29; mammals, animals) |
| Source | Ovis aries (Sheep) |
| Activity | Antimicrobial, Antibacterial, Antifungal |
| Pathogen | [Ref.8549789][No NaCl]: Escherichia coli DH5a (MIC=0.1 µM), Escherichia coli ML-35p (MIC=0.18 µM), Pseudomonas aeruginosa PAO1 (MIC=0.17 µM), Pseudomonas aeruginosa MR3007 (MIC=0.34 µM), Staphylococcus aureus ATCC (MRSA) 33591 (MIC=1.24 µM), Staphylococcus aureus 93918 (MIC=0.31 µM).##[100 mM NaCl]: Escherichia coli DH5a (MIC=0.07 µM), Escherichia coli ML-35p (MIC=0.12 µM), Pseudomonas aeruginosa PAO1 (MIC=0.08 µM), Pseudomonas aeruginosa MR3007 (MIC=0.18 µM), Staphylococcus aureus ATCC (MRSA) 33591 (MIC=0.65 µM), Staphylococcus aureus 93918 (MIC=0.43 µM). |
| Hemolytic Activity | [Ref.8549789]Not found |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P49928, P49929 |
| PDB | 1FRY |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 8549789, 11932493 |
Physicochemical Properties
| Residues | 29 |
|---|---|
| Sequence | RGLRRLGRKIAHGVKKYGPTVLRIIRIAG |
| Molecular Weight | 3255.956 |
| Grand Average of Hydropathy | -0.21 |
| Isoelectric Point | 12 |
| Charge at pH 7.4 | 8.584 |
| Secondary Structure | Helix: 0.345, Turn: 0.207, Sheet: 0.172 |
| Instability Index | 26.41 |
| Aromaticity | 0.034 |