Basic Information
| ID | DRAMP18617 |
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| Sequence | RGLRRLGRKIAHGVKKYGATVLRIIRIA |
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| Length | 28 |
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| Name | [A19]-SMAP-29 (SMAP-29 peptide derivative) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Anitifungal |
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| Pathogen | [Ref.11467858]Gram-positive bacteria: [No NaCl]: Bacillus subtilis (MIC=4.0 μM), Staphylococcus aureus (MIC=2.0 μM), Micrococcus luteus (MIC=2.0 μM), Staphylococcus epidermidis (MIC=2.0 μM);##[100 mM NaCl]: Bacillus subtilis (MIC=2.0 μM), Staphylococcus aureus (MIC=1.0 μM), Micrococcus luteus (MIC=2.0 μM), Staphylococcus epidermidis (MIC=1.0 μM).##Gram-negative bacteria: [No NaCl]: Escherichia coli (MIC=4.0 μM), Salmonella typhimurium (MIC=2.0 μM), Pseudomonas aeruginosa (MIC=16.0 μM);[100 mM NaCl]: Escherichia coli (MIC=1.0 μM), Salmonella typhimurium (MIC=1.0 μM), Pseudomonas aeruginosa (MIC=4.0 μM).##Fungi: [No NaCl]: Candida albicans (MIC=2.0 μM);[100 mM NaCl]: Candida albicans (MIC=16.0 μM). |
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| Hemolytic Activity | [Ref.11467858]7% hemolysis at 12.5 μM, 13% hemolysis at 25 μg/ml, 28% hemolysis at 50 μg/ml, 50.4% hemolysis at 100 μg/ml against human red blood cells |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 11467858 |
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