Basic Information

IDDRAMP03043
SequenceINWLKLGKAIIDAL
Length14
NameAgelaia-mastoparan (Agelaia-MP; Insects, animals)
SourceAgelaia pallipes pallipes (Neotropical social wasp)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.15225564]Gram-negative bacteria: Escherichia coli (MIC=382 µg/ml), Pseudomonas aeruginosa (MIC=257 µg/ml);##Gram-positive bacteria: Bacillus subtilis (MIC=237 µg/ml), Staphylococcus aureus (MIC=191 µg/ml).
Hemolytic Activity[Ref.15225564]70% hemolytic activity at 156 ng/ml against rat erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P69436
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15225564, 15052574

Physicochemical Properties

Residues14
SequenceINWLKLGKAIIDAL
Molecular Weight1567.912
Grand Average of Hydropathy0.886
Isoelectric Point8.591
Charge at pH 7.40.553
Secondary StructureHelix: 0.500, Turn: 0.143, Sheet: 0.357
Instability Index-7.5
Aromaticity0.071

Similar Structure Search

Candidates based on structure

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