Basic Information

IDDRAMP03187
SequenceQRYFCRVRGGRCAALTCLPRETQIGRCSVKGRKCCR
Length36
NameBeta defensin 1(BD-1; mammals, animals)
SourceChinchilla lanigera (Long-tailed chinchilla)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacterium: Moraxella catarrhalis (MIC=5 µg/ml);##Gram-positive bacterium: Streptococcus pneumoniae (MIC=5 µg/ml).##Fungi: Candida albicans (MIC=12.5-20 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P83943
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID14996845

Physicochemical Properties

Residues36
SequenceQRYFCRVRGGRCAALTCLPRETQIGRCSVKGRKCCR
Molecular Weight4132.918
Grand Average of Hydropathy-0.531
Isoelectric Point10.354
Charge at pH 7.48.404
Secondary StructureHelix: 0.194, Turn: 0.167, Sheet: 0.139
Instability Index12.05
Aromaticity0.056

Similar Structure Search

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