Basic Information

IDDRAMP03288
SequenceLPVNEAQCRQVGGYCGLRICNFPSRFLGLCTRNHPCCSRVWV
Length42
NameOstricacin-4 (Beta-defensin 8; Birds, animals)
SourceStruthio camelus (Ostrich)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus 1056-MRSA (MIC=11.48 µg/ml);##Gram-negative bacterium: Escherichia coli O157:H7 (MIC=12.03 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot P85116
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16459058

Physicochemical Properties

Residues42
SequenceLPVNEAQCRQVGGYCGLRICNFPSRFLGLCTRNHPCCSRVWV
Molecular Weight4754.551
Grand Average of Hydropathy0.031
Isoelectric Point8.983
Charge at pH 7.43.446
Secondary StructureHelix: 0.310, Turn: 0.286, Sheet: 0.143
Instability Index44.371
Aromaticity0.095

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