Basic Information

IDDRAMP03253
SequenceGKLQAFLAKMKEIAAQTL
Length18
NameM-lycotoxin-Ls3a (M-LCTX-Ls3a; Lycocitin-1; spiders, Arthropods, animals)
SourceLycosa singoriensis (Wolf spider) (Aranea singoriensis)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacteria: Staphylococcus aureus, Bacillus subtilis ATCC6633 (MIC=1.6-3.2 µM);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=3.2-6.4 µM), Pseudomonas aeruginosa.##Yeast: Candida albicans.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P0C2U6
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID14991689

Physicochemical Properties

Residues18
SequenceGKLQAFLAKMKEIAAQTL
Molecular Weight1961.372
Grand Average of Hydropathy0.25
Isoelectric Point9.703
Charge at pH 7.41.551
Secondary StructureHelix: 0.278, Turn: 0.056, Sheet: 0.500
Instability Index46.933
Aromaticity0.056

Similar Structure Search

Candidates based on structure

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