Basic Information

IDDRAMP03254
SequenceGRLQAFLAKMKEIAAQTL
Length18
NameM-lycotoxin-Ls3b (M-LCTX-Ls3b; Lycocitin-2; spiders, Arthropods, animals)
SourceLycosa singoriensis (Wolf spider) (Aranea singoriensis)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacteria: Staphylococcus aureus 209P, Bacillus subtilis ATCC 6633 (MIC=1.57-3.14 µM);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=3.14-6.29 µM), Pseudomonas aeruginosa ATCC 27853 (MIC=5.02-10.05 µM).##Fungi: Candida albicans.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P0C2U7
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID14991689

Physicochemical Properties

Residues18
SequenceGRLQAFLAKMKEIAAQTL
Molecular Weight1989.385
Grand Average of Hydropathy0.217
Isoelectric Point9.994
Charge at pH 7.41.554
Secondary StructureHelix: 0.278, Turn: 0.056, Sheet: 0.500
Instability Index56.367
Aromaticity0.056

Similar Structure Search

Candidates based on structure

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