Basic Information

IDDRAMP03287
SequenceIPRPLDPCIAQNGRCFTGICRYPYFWIGTCRNGKSCCRRR
Length40
NameOstricacin-3 (Beta-defensin 7; Birds, animals)
SourceStruthio camelus (Ostrich)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus 1056-MRSA (MIC=2.78 µg/ml);##Gram-negative bacterium: Escherichia coli O157:H7 (MIC=2.41 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot P85115
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16459058

Physicochemical Properties

Residues40
SequenceIPRPLDPCIAQNGRCFTGICRYPYFWIGTCRNGKSCCRRR
Molecular Weight4679.488
Grand Average of Hydropathy-0.473
Isoelectric Point9.691
Charge at pH 7.46.403
Secondary StructureHelix: 0.250, Turn: 0.275, Sheet: 0.050
Instability Index35.145
Aromaticity0.125

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