Basic Information

IDDRAMP02976
SequenceNIGNSVSCLRNKGVCMPGKCAPKMKQIGTCGMPQVKCCKRK
Length41
NameBeta-defensin 1 (BD-1; Defensin, beta 1; pigs, mammals, animals)
SourceSus scrofa (Pig)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Listeria monocytogenes, Streptococcus suis, Actinobacillus pleuropneumoniae;##Gram-negative bacterium: Escherichia coli.##Yeast: Candida albicans.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot O62697
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16552064, 9537511, 10446172

Physicochemical Properties

Residues41
SequenceNIGNSVSCLRNKGVCMPGKCAPKMKQIGTCGMPQVKCCKRK
Molecular Weight4398.409
Grand Average of Hydropathy-0.366
Isoelectric Point9.819
Charge at pH 7.48.393
Secondary StructureHelix: 0.146, Turn: 0.317, Sheet: 0.122
Instability Index96.229
Aromaticity0

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