| ID | DRAMP04670 |
|---|---|
| Sequence | KNIGNSVSCLRNKGVCMPGKCAPKMKQIGTCGMPQVKCCKRK |
| Length | 42 |
| Name | PBD1-42 |
| Source | Boletus edulis |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.23220638]Gram-negative bacterium: Escherichia coli (MIC=100 µg/mL);##Gram-positive bacterium: Staphylococcus aureus (MIC=80 µg/mL). |
| Hemolytic Activity | [Ref.23220638]5% hemolytic activity at 10 μg/mL, 10% hemolytic activity at 20 μg/mL, 10% hemolytic activity at 100 μg/mL against porcine fresh blood |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 23220638 |
Physicochemical Properties
| Residues | 42 |
|---|---|
| Sequence | KNIGNSVSCLRNKGVCMPGKCAPKMKQIGTCGMPQVKCCKRK |
| Molecular Weight | 4526.581 |
| Grand Average of Hydropathy | -0.45 |
| Isoelectric Point | 9.92 |
| Charge at pH 7.4 | 9.39 |
| Secondary Structure | Helix: 0.143, Turn: 0.310, Sheet: 0.119 |
| Instability Index | 94.176 |
| Aromaticity | 0 |