Basic Information

IDDRAMP03368
SequenceKKINNPVSCLRKGGRCWNRCIGNTRQIGSCGVPFLKCCKRK
Length41
NameBeta-defensin 3 (BD-3, mBD-3; Defensin, beta 3; Rodents, mammals, animals)
SourceMus musculus (Mouse)
ActivityAntimicrobial, Antibacterial, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli, Pseudomonas aeruginosa.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot Q9WTL0, Q29R78
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10377137

Physicochemical Properties

Residues41
SequenceKKINNPVSCLRKGGRCWNRCIGNTRQIGSCGVPFLKCCKRK
Molecular Weight4623.554
Grand Average of Hydropathy-0.598
Isoelectric Point10.35
Charge at pH 7.410.395
Secondary StructureHelix: 0.220, Turn: 0.317, Sheet: 0.049
Instability Index62.534
Aromaticity0.049

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