Basic Information

IDDRAMP03511
SequenceKWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKAL
Length35
NameCecropin-B (Immune protein P9; Insects, animals)
SourceHyalophora cecropia (Cecropia moth)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli D21 (MLC=0.32 µM), Escherichia coli D31 (MLC=0.32 µM), Serratia marcescens Db11 (MLC=4.5 µM), Serratia marcescens Db1108 (MLC=2.4 µM), Serratia marcescens Db1121 (MLC=2.2 µM), Serratia marcescens Strain 122 (MLC=2.9 µM), Pseudomonas aeruginosa OT97 (MLC=1.9 µM), Xenorhabdus nematophilus Xn21 (MLC=1.6 µM);##Gram-positive bacteria: Bacillus megaterium Bmll (MLC=0.44 µM), Bacillus subtilis Bs11 (MLC=18 µM), B.thuringiensis Bt11 (MLC>133 µM), Streptococcus fecalis AD-4 (MLC=7.3 µM), Streptococcus fecalis DS16 (MLC>24 µM), Micrococcus luteus M111 (MLC=1.3 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P01508
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID7140755

Physicochemical Properties

Residues35
SequenceKWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKAL
Molecular Weight3835.654
Grand Average of Hydropathy-0.071
Isoelectric Point10.729
Charge at pH 7.46.542
Secondary StructureHelix: 0.314, Turn: 0.200, Sheet: 0.286
Instability Index35.423
Aromaticity0.057

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