Basic Information

IDDRAMP03507
SequenceKWKIFKKIEKVGRNIRNGIIKAGPAVAVLGEAKAL
Length35
NameCecropin-B (Insects, animals)
SourceAntheraea pernyi (Chinese oak silkmoth)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Escherichia coli D21 (MIC=0.36 µM), Escherichia coli D31 (MIC=0.30 µM), Serratia marsescens (MIC=2.6 µM), Serratia marsescens Strain 122 (MIC=12 µM), Pseudomonas aeruginosa OT97 (MIC=2.9 µM), Xenorhabdus nematophilus Xn21 (MIC=1.6 µM);##Gram-positive bacteria: Bacillus subtilis Bsll (MIC=17 µM), Bacillus megaterium Bmll (MIC=0.64 µM), Bacillus thuringiensis Btll (MIC>88 µM), Streptococcus fecalis Ds16 (MIC>88 µM), Streptococcus fecalis AD-4 (MIC>88 µM), Micrococcus luteus MI11 (MIC=0.29 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P01509
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID6754375, 2962676

Physicochemical Properties

Residues35
SequenceKWKIFKKIEKVGRNIRNGIIKAGPAVAVLGEAKAL
Molecular Weight3817.616
Grand Average of Hydropathy0.003
Isoelectric Point10.729
Charge at pH 7.46.542
Secondary StructureHelix: 0.343, Turn: 0.200, Sheet: 0.257
Instability Index22.08
Aromaticity0.057

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