Basic Information

IDDRAMP03527
SequenceDKLIGSCVWGATNYTSDCNAECKRRGYKGGHCGSFWNVNCWCEE
Length44
NameGm defensin-like peptide (Insects, animals)
SourceGalleria mellonella (Greater wax moth)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
PathogenGram-positive bacterium: Sarcina Lutea (MIC=1.9 µM).##Fungi: Aspergillus niger (MIC=2.9 µM), Candida albicans (MIC=2.9 µM), C. fructus (MIC=2.9 µM), Candida wickerhamii (MIC=2.9 µM), Pichia pastoris (MIC=2.9 µM), P. stiptis (MIC=2.9 µM), Pachysolen tannophilus (MIC=2.9 µM), Trichoderma harzianum (MIC=2.9 µM), Zygosaccharomyces marxianus (MIC=2.9 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot P85215
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17194500

Physicochemical Properties

Residues44
SequenceDKLIGSCVWGATNYTSDCNAECKRRGYKGGHCGSFWNVNCWCEE
Molecular Weight4949.458
Grand Average of Hydropathy-0.655
Isoelectric Point6.732
Charge at pH 7.4-0.559
Secondary StructureHelix: 0.227, Turn: 0.295, Sheet: 0.136
Instability Index44.348
Aromaticity0.136

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