Basic Information

IDDRAMP00431
SequenceKTCMTKKEGWGRCLIDTTCAHSCRKYGYMGGKCQGITRRCYCLLNC
Length46
NameDefensin-like protein 2 (Cp-thionin II; Cp-thionin-2; Gamma-thionin II; Plant defensin)
SourceVigna unguiculata (Cowpea)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus ATTC 25923 (MIC=128 mg/ml);##Gram-negative bacteria: Escherichia coli ATTC 25922 (MIC=64 mg/ml), Pseudomonas syringae (MIC=42 mg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization of a C-terminal Cys residue (forming a disulfide bond)
Linear/Cyclic/BranchedCyclic
Uniprot P84920
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16824043

Physicochemical Properties

Residues46
SequenceKTCMTKKEGWGRCLIDTTCAHSCRKYGYMGGKCQGITRRCYCLLNC
Molecular Weight5242.227
Grand Average of Hydropathy-0.439
Isoelectric Point9.202
Charge at pH 7.46.379
Secondary StructureHelix: 0.196, Turn: 0.174, Sheet: 0.152
Instability Index42.059
Aromaticity0.087

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.