Basic Information
| ID | DRAMP00746 |
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| Sequence | RECKTESNTFPGICITKPPCRKACISEKFTDGHCSKILRRCLCTKPC |
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| Length | 47 |
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| Name | Flower-specific defensin (NaD1; Plant defensin) |
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| Source | Nicotiana alata (Winged tobacco) (Persian tobacco) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | Fungi: Fusarium oxysporum f. sp. Vasinfectum (IC50=1 µM), Thielaviopsis basicola (IC50=0.80 µM), Verticillium dahliae (IC50=0.75 µM), Leptosphaeria maculans (IC50=0.80 µM), Aspergillus nidulans (IC50=0.80 µM), Candida albicans (IC50>10 µM), Pichia pastoris (IC50>10 µM), Saccharomyces cerevisiae (IC50>10 µM).##Gram-negative bacteria: Escherichia coli (IC50>10 µM), Pseudomonas aeruginosa (IC50>10 µM);##Gram-positive bacteria: Staphylococcus aureus (IC50>10 µM), Bacillus cereus (IC50>10 µM).##HeLa cells (IC50>10 µM). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
Q8GTM0 |
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| PDB |
4AAZ, 4AB0 resolved by X-ray. |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 12644678, 12473460, 22511788, 18339623 |
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