Basic Information
| ID | DRAMP00398 |
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| Sequence | KFCEKPSGTWSGVCGNSGACKDQCIRLEGAKHGSCNYKLPAHRCICYYEC |
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| Length | 50 |
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| Name | Defensin D2 (Ns-D2; Plant defensin) |
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| Source | Nigella sativa (Black cumin) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | Fungi: Aspergillus niger (IC50=3.5 µg/ml), Bipolaris sorokiniana (IC50=1.8 µg/ml), Fusarium oxysporum (IC50=5.3 µg/ml), Fusarium graminearum (IC50=6.9 µg/ml), Fusarium culmorum (IC50=6.9 µg/ml) and Botrytis cinerea (IC50=13.7 µg/ml).##Gram-positive bacteria: Clavibacter michiganensis (1.5 cm) and Bacillus subtilis (1.3 cm);##Gram-negative bacteria: Pseudomonas syringae (1.3 cm), Erwinia carotovora (0.7 cm) and Escherichia coli (1.4 cm).##NOTE: Inhibition zone; Defensin concentration (11 µg in 50 μl). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
P86973 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 21144761 |
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